
Every innate immune reaction is a lesson on how to survive infections without dying in the attempt

The small big effectors in
epithelial defenses
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OUR LAB


Selected Publications

Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production.
Gut Microbes. July 2020
Cathelicidins mitigate Staphylococcus aureus mastitis and reduce bacterial invasion in murine mammary epithelium.
Infection and Immunity. 2020
A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.
Nature Medicine. 2012
Colonic MUC2 mucin regulates the expression and antimicrobial activity of β-defensin 2.
Mucosal Immunology. 2015
Human Cathelicidins Contribute Differently to Hallmarks of Mastitis Induced by Pathogenic Prototheca bovis Algae.
Frontiers in Cellular and Infection microbiology. 2020
Entamoeba histolytica Alters Ileal Paneth Cell Functions
in Intact and Muc2 Mucin Deficiency.
Infection and Immunity. 2018
MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis.
Infection and Immunity. 2017
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